le 28/10/2022


Global Grand Challenges – Accelerating Innovations in Non-Hormonal Contraception for Women

This RFP seeks innovations that contribute to development of safe and effective non-hormonal contraceptives that meet the needs and interests of women and that address key barriers in accessing and using currently available methods.

It is seeking non-hormonal contraceptives that are easy to access, discreet, convenient, and non-invasive. Additionally, it is important that these methods have tolerable side effects and do not impact the menstrual cycle.

This work will be led by Grand Challenges Africa, a program of the Science for Africa Foundation with funding support from the Bill & Melinda Gates Foundation.

The ultimate goal is development of novel non-hormonal female contraceptives that

  1. provide safe and effective contraception,
  2. do not contain sex steroid hormones or rely on hormonal mechanisms of action (e.g., do not impact the hypothalamic-pituitary-gonadal axis), 
  3. do not disrupt endogenous menstrual bleeding patterns, and
  4. are suitable and appropriate for use in LMICs.

The overall goal is to reduce the unmet need for contraception by enhancing contraceptive uptake, continuation, and satisfaction among reproductive aged adolescent girls and women who want to avoid pregnancy. Contraceptive product innovation is required to achieve this goal.

Objectives :

Advance novel and bold ideas that accelerate development of new non-hormonal female contraceptive candidates aligned with women’s preferences that are currently unmet. This includes, but is not limited to:

  • Formulation development or advances in materials science with application to non-hormonal female contraception
  • Pre-clinical development of non-hormonal female contraceptive candidates/leads
  • Development and/or testing of novel or optimized drug delivery systems with application to non-hormonal female contraceptives


Deadline : Friday, December 16, 2022

Funding : up to USD $350,000 and for up to 2 years

Further  information

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